Research Areas

  Pharmacology, Toxicology and Pharmacognosy

 

Cancer Pharmacology

Topic: Pharmacodynamics and pharmacokinetic aspects of cancer pharmacology, with special emphasis on discovery of novel molecular targets in cancer cells and in the non-cancerous cells forming the tumor microenvironment, cancer metabolomics, metabolite profiling and evaluation of drug-drug interaction potential of anticancer agents.
Researchers: Monica Montopoli; Lucia Trevisi, Luigi Quintieri.
Current research interests:

  • Selective induction of controlled cancer cell death
  • Pharmacologic modulation of angiogenesis
  • Cancer metabolism and drug resistance
  • Drugs targeting the tumor microenvironment
  • Cancer metabolomics
  • Drug metabolite profiling and assessment of potential metabolism-based drug-drug interactions

Pharmacognosy and Environmental Toxicology
Topic: Employement of medicinal plants of traditional use and their isolated phytoconstituents for hypoglycaemic, hypotensive, antiviral, antioxidant and antiageing purposes.
Researchers: Guglielmina Froldi

Peptide receptor Pharmacology
Topic: Advanced pharmacology of peptidergic systems, with particular attention to ligands acting on G protein-coupled receptors (GPCRs).
Researchers: Girolamo Calò; Davide Malfacini